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Losartan Potassium is an
angiostein II receptor (type AT1)antagonist. Losartan and its
principle active metabolite block the vasoconstrictor and
aldosterone secreting effects of angiostein II by selectively
blocking the binding of angiostein II to AT1.
The drug is used for treating High blood pressure and preventing
progression of kidney diseases in patients suffering from type 2
The drug acts by preventing the action of a hormone called
angiotensin II in the human body. Angiotensin II generally acts on
special receptors in the body, with two major results. One, it
narrows the peripheral blood vessels , and two, it stimulates the
production of hormone aldosterone, another hormone in the body.
Aldosterone hormone, causes salt and water to be retained by the
kidneys, there by increasing the volume of fluid in the blood
vessels. Losartan blocks the receptors that angiotensin II acts on, and so prevents its actions.
25-100 mg once or twice daily: starting and maintenance dose: 50 mg
once a day. In volume depleted patients: 25 mg once daily.
Hypersensitivity, pregnancy. Lactating
The drug has certain side effects, that can affect individuals in
different ways. The following are some of the side effects, that are
often associated with the drug:
Disclaimer: The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
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portal gives you extensive list of the cGMP contract manufacturer of herbals and
pharmaceutical manufacturing capabilities. It also contains the valuable information
pertaining to the drug manufacturing with the names of various drugs.
Under finished pharmaceutical formulations the drugs are manufactured
under strict quality control for ensuring a completely safe product. The
finished formulations are available in the form of tablets, capsules, injections.
Pharmaceutical Drugs are those drugs that are given under the
supervision of physicians to cure various physical disorders. They are
either prescriptive or non prescriptive.
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