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Streptokinase InjectionGeneric name: Streptokinase - injection
Brand name: Kabikinase, Streptase

Streptokinase has no effect on plasminogen. It acts upon by binding with plasminogen to form a 1:1 composite & turns in a participating enzyme plasmin. It is non-enzyme macromolecule acquired by certain strains of beta hemolytic Streptococci. It resolve clot mainly by converting the intrinsic plasminogen present in the fibrin clot to its active agent form plasmin.Streptokinase is called a thrombolytic agent and acts best when it is given soon after the approach of heart attack symptoms. Streptokinase can also break up blood clots that form in intravenous tubes . Generic streptokinase is not yet available.

  • Streptokinase is used to break up blood clots in the blood vessels of leg veins, lungs and around the heart.
  • Streptokinase injection can dissolve blood clots that form in the heart, blood vessels, or lungs after a heart attack, or some other disease process.
  • Used for intestinal disorder (short bowel syndrome)
  • It is also used to treat people who are having heart problems.
  • The medicine will be given intravenously through a tube that goes in one of your blood veins.
  • This medicine is very strong. Before taking it, one should be very clear as to why he is getting it and what are the risks and benefits of this treatment. It is important for you to follow your doctors orders strictly.
  • One will get this medicine in a hospital, so the results of his treatment can be watched closely.
  • Your doctor will prescribe your dose and tell you how long it will be given.
Safety tips
  • One should not take this medicine if he ever had an allergic reaction to streptokinase.
  • This medicine should not be taken, if a person has high blood pressure or bleeding disorders.
  • Your doctor should be aware of conditions like endocarditis, recent biopsy or surgery, recent injury, any allergies.
  • You should use extra caution to avoid injury and trauma (e.g., carefully brush teeth) while using this medication due to the increased risk of bleeding.
  • This medicine should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
Common side effects
Some of the side effects that occurs due to improper intake of Streptokinase are as follows:
  • Nausea
  • Dizziness
  • Low blood pressure or mild fever
  • Nerve damage.
  • Headache
  • Flushing, rapid or abnormal heartbeat, chest pain.
  • Blood in your urine or bowel movements (or black tarry stools)
  • Bloody vomit or vomit that looks like coffee grounds
  • Nosebleeds or bleeding from any area
  • Purple spots on skin or unexplained bruises
  • Wheezing or trouble breathing
  • Skin rash, itching, or hives
  • Swelling in the face, lips, or mouth
  • Streptokinase should be stored in a cool dry area as directed. Discard any unused medication after the expiry date on the label. Keep this drug out of
  • reach of children
Disclaimer:The above information is for general understanding of the visitor. Please consult a registered medical practitioner before taking the aforesaid medicine.

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