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Vinblastine - injection
Vinblastine is a drug used to treat certain types of cancer.
Vinblastine is available under the trade names Velban and Velsar, and may also be referred to as vinblastine sulfate. It is a
naturally occurring compound that is extracted from periwinkle
plants. It belongs to a group of chemicals called alkaloids.
Vinblastine prevents the formation of microtubules in cells. One of
the roles of microtubules is to aid in the replication of cells. By
disrupting this function, vinblastine inhibits cell replication, including the replication the cancer cells.
How to use
- It is used in treatment of cancer to slow or stop the growth
of cancer cells.
- Helps in removing drug from body and some side effect in
- Vinblastine is a cytotoxic drug that arrests cell growth at
the metaphase. Its actions are more pronounced on the rapidly
dividing cell than on the normal cell.
- Vinblastine is excreted slowly in urine and in faeces via the
- Vinblastine is rapidly cleared from the blood and distributed
into the body tissues. It crosses the blood-brain barrier poorly
and does not appear in the CSF in therapeutic concentrations
- Vinblastine is extensively metabolised by the liver. It is
converted to desacetyl-vinblastine which is more active on a
weight basis than the parent compound.
This medication is a potent medication. Use it exactly as
prescribed. Tell your doctor immediately if you experience burning
or redness, pain at the place where injected. It inhibits
microtubule formation in the mitotic spindle thus arresting cell
division in metaphase. As vinblastine is administered intravenously, the site of infusion and surrounding tissue should be monitored for
signs of inflammation and irritation.
If vinblastine is accidentally leaked, the skin or muscle can be
- Notify your doctor immediately if you feel pain or irritation
at the injection site.
- Fatalities have occurred when vinblastine was injected into
the spine. This drug is for intravenous (IV) use only.
- While taking this medication drink plenty of fluids.
Contact your doctor immediately if you experience any of the
- Joint pain
- Swelling of feet or lower legs
- Black/ tarry stools
- Painful or difficulty in urination
- Sores in mouth or lips
Some common effects are :
Disclaimer:The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
- Muscle pain
- Temporary hair loss
- Lowers resistance power
- Difficulty in walking
- Sensory loss
- Weight loss
- Skin ulceration
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pertaining to the drug manufacturing with the names of various drugs.
Under finished pharmaceutical formulations the drugs are manufactured
under strict quality control for ensuring a completely safe product. The
finished formulations are available in the form of tablets, capsules, injections.
Pharmaceutical Drugs are those drugs that are given under the
supervision of physicians to cure various physical disorders. They are
either prescriptive or non prescriptive.
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