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Zoledronic acid is a white powder. Its molecular formula is
C5H10N2O7P2 H2O. Zoledronic acid is highly soluble in sodium
hydroxide solution, sparingly soluble in water and hydrochloric
acid, and practically insoluble in organic solvents. The pH of a
0.7% solution of Zoledronic acid in water is nearly 2.0
- Zolendronic Acid is used in the treatment of bones
(hypercalcemia of malignancy) caused by cancer.
- It is used in the treatment of patients with multiple myeloma
and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy.
- It is also beneficial during ocular inflammation such as
uveitis and scleritis.
- Zoledronic acid minimizes the discharge and breakdown of
calcium from bone. It is used when high amount of calcium is
found in the blood of the patient to lower the blood calcium
levels. High blood calcium levels can make the person confused
and tired which results into continuous stomach pain and muscle
weakness. Zoledronic acid helps to relieve these symptoms.
- Zoledronic acid is also used to prevent chances of bone
Zoledronic acid is for injection or infusion into a vein. It is
given by a healthcare professional, usually in a hospital or clinic
setting. The maximum recommended dose of zoledronic in hypercalcemia
of malignancy is 4 mg. The 4-mg dose must be given as a single-dose
intravenous infusion over no less than 15 minutes. Patients who
receive it, should have serum creatinine assessed prior to each
treatment. Dose adjustments are not necessary in treating patients
for hypercalcemia of malignancy presenting with mild-to-moderate
renal impairment prior to initiate the therapy.
Common side effects
- Your doctor should know if you are suffering from aspirin
sensitive asthma, kidney or dental disease.
- Your doctor should also be informed if you have allergy from
Zoledronic acid or any other medicines or chemical, or you are
pregnant or doing breeast feeding.
- Visit your health care professional for regular check ups.
- You should talk with your doctor about your dietary or
- You should not take supplements without your doctor's advice.
- Your Doctor should be aware of your medical history.
Following are the few side effects which occurs due to improper
dose and different radiations.
Disclaimer:The above information is for general
understanding of the visitor. Please consult a registered medical
practitioner before taking the aforesaid medicine.
- constant jaw pain, especially burning or cramping
- eye inflammation, pain, or vision change
- muscle cramps or weakness
- pain or difficulty passing urine
- very stiff muscles, unable to move easily
- bone pain
- nausea, vomiting
- loss of appetite
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portal gives you extensive list of the cGMP contract manufacturer of herbals and
pharmaceutical manufacturing capabilities. It also contains the valuable information
pertaining to the drug manufacturing with the names of various drugs.
Under finished pharmaceutical formulations the drugs are manufactured
under strict quality control for ensuring a completely safe product. The
finished formulations are available in the form of tablets, capsules, injections.
Pharmaceutical Drugs are those drugs that are given under the
supervision of physicians to cure various physical disorders. They are
either prescriptive or non prescriptive.
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